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    HPS Ingredient Spotlight

    Ingredient Spotlight GS4 PLUS (Gymnema Sylvestre)

    Ingredient Spotlight GS4 PLUS (Gymnema Sylvestre)

    Chances are, if you have used any sort of nutrient partitioner product/GDA (glucose disposal agent) or carb blocker in the past, you have used some form of Gymnema Sylvestre before. However, Glycøshield uses a patented form called GS4 Plus, and is the only form that is extensively studied and proven to be effective.


    Gymnema Sylvestre, also known as the “Miracle Fruit”, is a vine that grows in tropical areas of Southern Asia, Africa, and Australia.  The leaves of this plant are what is considered a miracle, as they contain gymnemic acids, a compound that suppresses the taste of sweetness while not inhibiting any other flavors.  Not only does it suppress your cravings for sweet foods but it also has a host of benefits including blood sugar control, weight loss, improved GI functioning, antioxidant, antiatheroslerotic properties, and many more! One of the coolest things about supplementing with Gymnema Sylvestre is that it is not necessary to cycle off or take a break from use.  In fact, a 2004 study did a 52-week test of Gymnema supplementation and found no adverse health effects to the body at the end of the experiment (1)


    Keep reading below to find out why GS4 Plus is such an important component of Glycøshield!


    Glucose Manipulation:  Quite possibly the most popular, well known, and well examined use for GS4 Plus has been its ability to lower blood sugar. Much like berberine and Salaretin, GS4 Plus has been used almost regularly in studies as an alternative for prescription diabetes medications.  The Gymnemic acids found within the GS4 Plus work a few different ways to ensure blood sugar is regulated properly.  A recent study suggests that  gymnemic acid delays glucose absorption into the blood stream.  Due to the molecular arrangement of gymnemic acid and its similarity to glucose molecules, it fills the receptor locations on the taste buds to stop absorption at the initial area for carbohydrate breakdown and absorption; the mouth (2).  


    In a similar fashion, this same process also occurs in the external layers of the small intestine, which is also where glucose can be absorbed into the blood stream.  By preventing the absorption of glucose at its final destination before excretion, GS4 is also known as a carb blocker the same way Salaretin is.


    The second key biological factor that allows GS4 Plus to regulate glucose is through its stimulation of the pancreas.  Clinical trials have shown that GS4 stimulates the pancreas and thus increases insulin release (3).  For someone with diabetes who cannot produce enough insulin this will ensure blood glucose is removed from the blood stream and sent to muscles, organs, and cells to be used as energy and prevent hypoglycemia.  For individuals who use GS4 Plus and do not have diabetes, this will only enhance the insulin response within the body and allow for more glucose to be shuttled into muscles, organs and cells.  Once those are full, it will work to move the rest of the glucose through the GI tract to be excreted.  The study also found that over time, when coupled with Hydroxycitric acid / Garcinia Cambogia (found in the Lipøshield and Glycøshield) GS4 Plus can help to reduce your fasting blood glucose levels as well.  Talk about a complete glucose regulator!


    Weight Loss: Aside from controlling blood glucose levels, GS4 Plus has other mechanisms that help individuals suffering from obesity as well as those who are at risk for it.  A 2014 study found that Gymnemic acid can prevent accumulation of triglycerides in muscle and the liver, while also decreasing fatty acid accumulation in the blood (4).  This also has huge implications for general health as those who are not at risk for obesity but have high levels of triglycerides are at a higher risk for a stroke!  This feature of GS4 Plus will ensure that excess fatty acids in the blood stream do not affect arteries and keeps them from being stored as, resulting in less fat gain. Another recent study from 2017 showed individuals supplementing with JUST 600mg of Gymnema Sylvestre over the course of 12 weeks reduced their body weight, their BMI measure, and LDL cholesterol as well (5).  The biggest kicker about this particular study? Subjects also had their insulin sensitivity and insulin secretions monitored during this period and at the end of the study were found to have no permanent increase in insulin secretion or insulin sensitivity.  While increased sensitivity is claimed to be good for some (meaning less released insulin is more effective and regulating blood glucose), it is important to understand that GS4 Plus does not permanently alter the way your pancreas and liver work.  



    Anti-Inflammatory/Cardioprotective abilities


    Last but certainly not least, yet another one of the ingredients we use has some sort of cardioprotective and anti-inflammatory property.  Quickly mentioned above how GS4 Plus has the ability reduce triglyceride storage and build up in the arteries, it is also known for lowering serum cholesterol levels.  One study suggests that Gymnema can also lower arterial blood pressure, lower resting heart rate, and serum leptin levels in as little as 28 days (7).  The bioactive saponins and tannins within GS4 Plus were found to decrease edema and inflammation of tissues almost as well as the nonsteroidal anti-inflammatory drug (NSAID) Phenylbutazone. 


    To recap, GS4 Plus can regulate blood glucose levels, play a role in insulin control, reduce sweet cravings, directly and indirectly impact obesity levels, protect the cardiovascular system, and play a role in the immune system / anti-inflammatory response.  GS4 Plus really does it all when incorporated into your supplement regimen.  



    1- https://www.ncbi.nlm.nih.gov/pubmed/15168555

    2- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170951/#B10

    3- https://www.ncbi.nlm.nih.gov/pubmed/10556769

    4- https://www.ncbi.nlm.nih.gov/pubmed/24166097

    5- https://www.ncbi.nlm.nih.gov/pubmed/28459647


    7- https://www.ncbi.nlm.nih.gov/pubmed/23112423

    Ingredient Spotlight: Banaba Leaf (10% Corsolic Acid)

    Ingredient Spotlight: Banaba Leaf (10% Corsolic Acid)

    By now you should know that we believe in using ingredients here at HPS that are multi-faceted, can help you achieve your goals, and also improve your overall health.  The supplement we are spotlighting next is no different than the ones that preceded it.  Enter Banaba Leaf extract, another ingredient aimed at controlling blood glucose levels, promoting an anti-obesity environment, and improving overall health aspects such as anti-inflammatory properties, anti-viral properties, and antioxidant properties, to name a few.  


    Banaba Leaf extract is standardized for 10% Corsolic acid and is taken directly from the leaf of the plant.  This plant is native to the tropical areas of southern Asia and has been used for many years in that region.  The Banaba leaf, in some regions, is consumed whole as if it were a vegetable, steeped in teas, and the mature fruits have even been used for traditional medicine.  So why do we love this ingredients?  Keep reading to find out some of the most important benefits that come with Banaba Leaf extract.


    Glucose control:

    This first aspect may be the most important and most studied aspect of Corsolic acid, Glucose control.  The Banaba Leaf extract has numerous functions that help it to control glucose and fix blood sugar levels.  One of the biggest impacts Corsolic acid makes is the speed at which it can reduce blood sugar levels.  Studies suggest that pure Corsolic acid can decrease blood sugar levels in humans within 60 minutes of consumption(1).  This is yet another reason we want users to take GlycoShield around 30 minutes prior to a meal; because of its ability to quickly lower blood sugar levels, especially after high carbohydrate meals. In fact, one clinical study evaluated the effects of using just 100mg of Banaba extract daily with 15 different subjects and found an average of a 16.6% decrease in fasting blood glucose levels (2).  Subjects who had a fasting glucose level above 110mg/dL had an even larger decrease during that study. 


    One of Corsolic acid’s main mechanisms is the prevention of glucose absorption in the intestine.  You may begin to see a trend here between some of our ingredients: a lot of preventative action in the small intestine.  The reason that this is so important is because it is the last line of defense after glucose passes through the GI tract.  Glucose has so many ways it can be absorbed and stored that it is crucial the remaining glucose in the intestine is not stored as fat, but neutralized and excreted instead. 


    Although occasional studies with this ingredient are performed on individuals with diabetes or pre-diabetes, many studies also suggest similar positive effects for those who are not diabetic.  A clinical trial performed by 12 nondiabetic subjects who all had a baseline blood glucose level of 104 mg/dL were tested for 2 weeks.  During this time, they were given 1 softgel capsule that contained 10mg of Banaba leaf extract that was standardized to 18% Corsolic acid.  By the end of the study, individuals had an average of a 12% decrease in fasting and post meal blood glucose levels as well as an average 3lb loss per each person (3)!  Just as a reference for how powerful Banaba leaf extract can be; the standardized extract in the study comes out to 1.8mg of pure Corsolic acid (18% of a 10mg dosage); GlycoShield contains 150mg standardized to 10% Corsolic acid or 15mg.  If those individuals were able to reduce fasting blood sugar and post meal blood sugar by 12% over two weeks, can you imagine the damage control that 15mg of Corsolic acid can provide you for a massive cheat meal or diet that is regularly high in carbs?  We can, and that’s why we included it in GlycoShield.


    Anti-Obesity Effects:

    Obviously controlling glucose, blood sugar levels, and preventing the storage of excess glucose as fat is one way to control obesity, but Corsolic acid definitely has other mechanisms to control and prevent obesity as well.  Studies suggest that Corsolic acid plays a role in enhanced cellular uptake of glucose, impaired hydrolysis of sucrose and starches, decreased gluconeogenesis, and regulation of lipid metabolism (4).  In 1996 a major study was conducted regarding the effects of Banaba leaf extract with regards to weight management and triglyceride levels.  This study used a 5% Banaba leaf extract in a water solution over the course of the study.   The conclusion showed that this 5% water extract mixed with food reduced body weight by an average of 10%, and lowered liver triglyceride content by an average of OVER 40%(5)!  As if the anti-diabetic properties were not enough, it now has direct components that can help to lower triglyceride levels as well. This study also suggested that Banaba Leaf extract is confirmed to be anti-adipogenic.  This means that unlike insulin, which is adipogenic (catalyst to the creation of fat cells) Banaba Leaf extract has the ability to control blood glucose levels without increasing fat cell formation. The 150mg dose in a serving of GlycoShield standardized for 10% Corsolic acid is generally more than is used in many of these studies and thus is capable of producing much greater results.  The most important thing about all of these studies is that despite the rigorous testing, long dosing periods, and quantity of the dose, Banaba Leaf extract has been identified as safe and having no side effects. 


    Supplement safety/Synergistic Effects/General Health and wellness:

    The last aspect of Banaba Leaf extract that impresses us, is its long-term safety and general health benefits it provides, as well as evidence that proves its synergistic ability enhances other ingredients with similar effects.  We mentioned glucose control and anti-obesity properties but also mentioned that Banaba leaf has been known to have antihyperlipidemic (drugs known to treat high levels of fat such as high cholesterol), antioxidant, anti-inflammatory, antifungal, antiviral, antineoplastic (inhibition of tumors) and osteoblastic properties (6).  Many of these effects occur in everyday life, even if you pay attention to diet and exercise. When we mentioned its synergy ability, we made sure to research what it synergizes best with to ensure you are getting the most out of GlycoShield.  We found that many studies combined Banaba Leaf Extract with tannin components (like the ones found in Gymnema Sylvestre), Hydroxycitric acids (such as the ones found in Garcinia Cambogia) and oleuropeins (the compound found in olive leaf extract) (7).  You will notice that all 3 of those compounds are found in GlycoShield, and Garcinia is also found in Lipøshield.  Synergistic effects of Banaba leaf are so astounding, that one study combined Banaba extract, bitter melon extract (synephrine), Gymnema extract (GS4) Garcinia Cambogia extract, Bioperine (an improved absorption ingredient), an amylase inhibitor (enzyme to prevent starch breakdown) as well as elemental chromium, vanadium, and magnesium (important minerals for general health.  After 12 weeks of this particular “stack”, subjects lost an AVERAGE of 6.29kg (13.8lbs) including 3.72kg (8.2lbs) of body fat determined by a bioelectric impedance body fat monitor (8). Now how impressive is that?


    So, what have we established with Banaba Leaf Extract? For one, it is an excellent compound to regulate and lower blood sugar in as little as 60 minutes.  It has the ability to block glucose absorption in the lower intestine, and has been tested to work efficiently in both diabetic and non-diabetic subjects.  Its mechanisms enable it to control lipid metabolism and lower triglycerides while ensuring subjects do not go into a hypoglycemic state (too low of blood sugar).  It possesses numerous characteristics that allow it to improve facets of everyday life, whether its lowering inflammation or acting as a powerful antioxidant to rid the body of free radicals and toxins.  Of course, last but not least, it is completely safe to be dosed for an extended period of time and combined with other ingredients that it can potentially enhance the properties of!  What isn’t there to love about Banaba Leaf extract?  We hope you enjoyed learning a FEW of the benefits that come along with Banaba Leaf Extract and Corsolic acid.  





    5- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176148/

    Ingredient Spotlight: Raspberry Ketones

    Ingredient Spotlight: Raspberry Ketones

    We think it is about time to address the elephant in the room, or rather the ingredient; raspberry ketones.  Raspberry ketones, or RK as we will call it for short, have had quite the roller coaster of reviews since it made a big splash in the supplement market about 5 years ago.  At first it was touted as a miracle ingredient labeled as the next big product to combat obesity and aid in weight loss. Then, two years later it was ridiculed as the most useless supplement on the market and the only thing it made lighter, was your wallet.  We have done the research, read the studies, and think it is important to address what raspberry ketones are and what they do; because they ARE beneficial. 


    First, Raspberry ketones are a natural phenolic compound, which gives the aroma of red raspberries.  The odd thing is, raspberry ketones aren’t just found in raspberries, they are found in other fruits such as cranberries, and blackberries as well. RK do not have a lot of quality studies done on them which makes it tough to judge effectiveness relative to the claims made about them. However, numerous clinical trials as well as anecdotal evidence has been sited showing that RK has the ability to suppress appetite, improve lipolysis and fatty acid breakdown, and provide other anti-obesity actions.  Let’s take a look at why we use raspberry ketones, and what you can truly expect from this ingredient.


    Appetite Suppression:


    Appetite suppression can be a touchy subject to study because hunger is subjective and can be altered by a variety of things.  We were able to locate a study that put RK to the test against other ingredients that claimed to suppress appetite to determine whether or not it was actually a benefit. A 2018 study tested food consumption over the course of 2 hours after ingesting raspberry ketones.  This study showed that dosing raspberry ketones before a meal caused a 79.4% reduction in food consumed an hour later (1)!  In fact, out of the 6 different ingredients tested, only one, named UP601, showed a greater appetite suppressant effect than raspberry ketones. As listed on the label with Lipøshield, you can either use this with a meal, or before a meal, or even an ingredient in a meal.  We have had positive feedback from individuals who use Lipøshield anywhere from 30 minutes to an hour before eating. Many anecdotal reviews state that appetite suppression hits hard, and lasts, especially if you are looking to cut cravings mid-day.  This can play a huge role in any diet plan where you are counting calories, or even in everyday life to help you make smarter choices.


    Anti-Obesity effects:


    While appetite suppression can be catalyst to anti-obesity effects, raspberry ketones provide other benefits that can lead to weight reduction as well as prevent weight gain.  One aspect RK can help with is improved lipolysis and translocation of hormone-sensitive lipase from cytosol, to lipid droplets. Lipolysis is the breakdown of fats and fatty acids while translocation of hormone-sensitive lipase is essentially the movement of lipase (the enzyme that breaks down fatty acids) is moved from the cytosol (the cytoplasm within the cell) to fats.  A 2005 study showed that RK increased norepinephrine-induced lipolysis that was associated with the movement of the hormone-sensitive lipase (2).  After a 6 week trial it was found that RK enhanced fat metabolism, decreased body weight, decreased the weight of the liver (fatty liver) and lowered triglycerides in the blood. This major benefit is also important to look at when considering that yet another ingredient we use in our Shielded Stack has the ability to reduce fatty liver and lower triglyceride counts.  This makes raspberry ketones more than just an anti-obesity ingredient; it can be considered as a general health ingredient for those who have a history of high triglyceride levels, family heart health, or a history of pancreatitis or other pancreatic ailments.



    Raspberry ketones have also been studied at the genetic level to find what role it plays with certain adipogenic (fat creating cells) gene expressions.  A 2015 study tested RK to determine by which mechanism it works to improve lipid metabolism. The study found that adipocytes (fat cells) treated with RK suppressed the expression of major genes involved in the adipogenesis pathway, while also suppressing fat accumulation (3). This study concluded that raspberry ketones can inhibit the production of fat cells at the GENETIC level! For those who may store fat easier or in specific areas, raspberry ketones could potentially help to reduce the production of fat cells in those ‘problem’ areas, most typically around the waist and thighs/glutes! Now, we do not claim that raspberry ketones or Lipøshield will spot reduce the places where you hold fat but the studies have shown that it can reduce the amount of fat cells that are created throughout your body.


    Lastly, but definitely one of the most important aspects that RK has shown, is its potential to turn white adipose tissue (WAT) to brown adipose tissue (BAT).  These two types of fat have completely different purposes with the body, with brown fat generally helping the body to produce heat and thermogenesis; it is the “good fat”. On the opposite side, white fat is generally stored, and frequently found around the mid-section, certain small bones, and heart; and contrarily named the “bad fat”.  White fat commonly leads to cardiovascular disease, obesity, diabetes, and a long list of other diseases. In a 2018 study conducted on RK effects, research showed that through a few biological mechanisms, RK has the ability to have a “browning” effect on white fat, converting white fat to brown fat. It was found that RK increased mitochondrial biogenesis and the expression of browning-specific proteins and lipolytic enzymes (4).  Through these different effects, it was concluded that the supplementation of raspberry ketones can be very effective at treating obesity, especially in the mid section!  


    By using Lipøshield regularly, especially if you are carrying additional fat around your waist, you will benefit from white fat “browning” and potential to have it burned as energy rather than being stored.  While more mechanisms are still being studied and discovered, this is by far one of the biggest reasons we chose to include raspberry ketones into Lipøshield.


    We have done the research, read the studies, and have concluded that yes, Raspberry Ketones provide a variety of health benefits, especially when it comes to anti-obesity and weight reduction properties.  This ingredient has been put in the doghouse for years and frowned upon after its shining moment, but we feel it is a great addition to those looking to lose body fat and change their overall body composition. We found raspberry ketones also provide a great satiety benefit within Lipøshield, and help to reduce our appetite and food consumption, especially when taken before a meal.  User feedback has reported many of the same effects we have mentioned here, and we are confident that this ingredient will no longer be looked at useless but as a gateway to reducing obesity and improving weight loss.



     1- https://www.ncbi.nlm.nih.gov/m/pubmed/29443598

    2- https://www.researchgate.net/publication/7874790_Anti-obese_action_of_raspberry_ketone

    3- https://www.ncbi.nlm.nih.gov/pubmed/25429790

    4- https://www.ncbi.nlm.nih.gov/m/pubmed/29525531/

    Ingredient Spotlight: Salaretin (Salacia reticulata)

    Ingredient Spotlight: Salaretin (Salacia reticulata)

    This week’s supplement spotlight is back with another HUGE role player in our product GlycoShield.  Salacia reticulata, or the registered form we use in GlycoShield, Salaretin, has numerous benefits in regards to weight regulation, fat burning, and glycemic control.  Not to mention this ingredient also has strong anti-oxidant properties and currently has numerous studies being worked with regards to cholesterol control and beneficial effects to vital organs.  This compound is derived from a plant located in dry zones of southern Asia, specifically Sri Lanka.  While the plant produces flowers and seeds that do resemble almonds in size and shape, the real useful ingredient is derived directly from the plant itself rather than the fruit it bears.  So, what exactly makes this product so important in a GDA like GlycoShield?  In short, Salaretin has an amazing ability to manipulate your blood glucose and insulin after meals, especially ones containing a large amount of carbohydrates.  Let’s dive in to what makes Salaretin such a special ingredient and one of our all-timefavorites to supplement with!

    Salaretin’s Blood Glucose Control:

    Salaretin’s biggest and most beneficial property is its ability to reduce the body’s absorption of carbohydrates and reduce the spike in blood glucose and insulin following a meal.  A 2005 study used all non-diabetic individuals to test how the Salacia plant would affect blood glucose levels after a relatively high meal.  The study concluded that after consuming the meal (14g fat, 82g of carbohydrates, and 20g of protein) the individuals who were administered Salacia reduced their blood glucose levels 23% and serum insulin levels 29% (1)!  On the flipside of this, when tested on individuals who had diabetes, a dosage of just 240mg of Salacia had lowered blood glucose levels and insulin response 14%(2).  Here is a quick rundown of why this is important.  When we consume a meal or carbohydrates in general, your blood glucose levels rise.  This rise in blood glucose causes your body to release insulin into the blood stream which travels to cells and enables them to open up and accept glucose. When the glucose enters cells, it can be used for energy in the muscles, body functions, or stored to be used for later.  The more carbohydrates that are consumed, the more insulin needs to be released in order for the cells to absorb them and use them as energy later.  There comes a point when the body cannot use those 250g of carbohydrates you just ate and then the remaining glucose is stored, generally as fat if not within the muscles.  Due to Salaretin’s ability to both prevent absorption of excess carbohydrates(glucose) as well as its ability to then manipulate how high your blood glucose levels are, it can aid in the prevention of excess glucose being stored as fat.  In short, Salaretin makes sure that your carbohydrates are sent to where they need to get to, and anything extra is not being absorbed in the small intestine.  This brings us to the other reason that Salaretin is such an awesome ingredient:

    Salaretin’s direct effect on obesity and “carb blocking” ability.

    So, we have established that Salaretin has the ability to manipulate your blood glucose and insulin levels by moving excess glucose through the body without distributing it into the blood stream, but did you know it can actually BLOCK absorption of excess carbohydrates? Salaretin has the ability to act as a glucosidase inhibitor to prevent absorption of carbohydrates in the small intestine.  A specific study on Salaretin has shown that the extract has the ability to inhibit an enzyme called amylase (amylase breaks down complex carbohydrates like starches) and prevent the digestion of starches in the small intestine (3).  If complex carbohydrates are not broken down in the small intestine they continue to pass along the intestinal tract and eventually are excreted from the colon.   Essentially, Salaretin will not only help you get the most out of your carbohydrate meal by shuttling glucose into the muscles and cells that use it for energy, but once your body is full it will continue to pass those carbohydrates through your body to be excreted at a different time.  Because of this carbohydrate controlling property, Salaretin plays a key roll in preventing obesity in otherwise healthy adults. A 2014 study showed that during a study of Salacia’s effect on obesity and metabolic disorders, Salacia Reticulata produced a reduction in body weight, mesenteric fat accumulation (fat around the mesentery webbing of intestines), an improvement in abnormal glucose metabolism, and an increase in adiponectin (a protein hormone that regulates glucose and fatty acid breakdown) in blood plasma (4).  All of these benefits directly impact your ability to burn fat, as well as keep fat off, especially during periods where you may be bulking.  Other studies have shown that in as little as 4 weeks, individuals supplementing with a dose of 600mg per day and using regular exercise showed a reduction of 6.1% weight loss and 4.5% reduction in bodyfat(5).  This study just shows how potent combing Salaretin can be when coupled with exercise—in fact, the study did not even note that changes were made in eating habits (how cool is that?)!

    The bottom line is, we love Salaretin for everything it does, and continues to do.  It has so much science backing up the claims and is evident in so many user trials.  In fact, our CEO and numerous consumers of GlycoShield have taken time lapse photos of their blood glucose levels to prove the effects that Salaretin has after meals!  It is certainly a strong ingredient, even at a modest dose.  Not only have we seen users who have controlled glucose and insulin levels after huge meals but we have had numerous individuals comment on unexpected weight loss without any changes in their diet.  Some individuals have even lost weight during what they thought was a bulking phase!  All this and more is possible with Salaretin.  If you haven’t fallen in love with this ingredient yet, feel free to take a look at some of these websites and our favorite studies to learn more about one of our favorite ingredients in GlycoShieldIf you’relooking to indulge in a few guilt free cheat meals every month, prime your body with fuel for a tough workout, making sure you’re cementing those hard-earned gains, or looking to drop a little extra body fat without needing to start a fad diet, Salaretin has a benefit for you.  Just another way you can #BeatTheCheat with HPS Supplements.







    3- http://salaretin.com/inhbts.htm 

    4- https://www.ncbi.nlm.nih.gov/pubmed/24838513

    5- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351933/

    Ingredient Spotlight: Olive Leaf Extract (oleuropein)

    Ingredient Spotlight: Olive Leaf Extract (oleuropein)

    If you have tried different diet’s in the past, you more than likely have heard of the Mediterranean diet. This diet is rich in Mediterranean style foods such as yogurts, olives, certain breads, fish, and lamb. While all diets really come down to a matter of calories in vs. calories out, the Mediterranean diet does have something that most others can’t offer.  Due to the higher amount of olive oil, and olives included in the Mediterranean diet, your body will get a nice little boost of Oleuropein.  Oleuropein is an amazing compound with tons of benefits that is found mainly in olive oil and the leaves from olive trees.  While the biological mechanisms by which this compound works is still being investigated, we have found a whole host of benefits that stem from increased consumption of Oleuropein.  Some of which include anti-inflammatory effects, anti-cancer effects, anti-tumor aids, antioxidant activity, blood glucose benefits, and even neuroprotective benefits!  While most of those are great, we are going to focus on a few that make it a star ingredient in GlycoShield.  


    Antioxidant/Anti-Inflammatory Effects:

    Oleuropein has an interesting mechanism that creates an anti-inflammatory effect, neuroprotective, and regenerative effect.  In a 2017 study that tested various effects related to oleuropein supplementation, one study suggested that it can reduce oxidative damage in the area of the brain that is most affected by neurodegeneration in Parkinson’s disease (1).  Studies also suggest that oleuropein is the ONLY anti-inflammatory component that can be extracted from olive leaves and be effective at a low concentration (2).  Why are the anti-inflammatory properties worth mentioning now, and especially in a product like GlycoShield?  Well, it is worth mentioning that the “Western Diet” that so many of us are a part of, is filled with processed food, high carbohydrates, sugars, and trans fats, which isn’t always the healthiest of options.  Numerous studies have shown that eating in this way can cause inflammation, both at the muscular level as well as within the joints, gut, and even of the organs such as liver and pancreas.  Oleuropein’s ability to cut inflammation makes it a key component of GlycoShield by preventing inflammation from occurring due to poor diet.  Not all individuals experience inflammation when eating large amounts of carbohydrates, however following the dosing guide on the label, you can ensure that your body is receiving a clinically tested dose of Oleuropein to prevent any inflammation that may occur, especially when consuming that large cheat meal!


    Cardiovascular and Blood Pressure Effects:

    Quite possibly the most well-known effect of Oleuropein is its ability to treat high blood pressure and create a positive effect on cardiovascular health.  This benefit of Olive Leaf Extract has been one of the top researched and studied benefits of Oleuropein in the last 10 years.  As we said before, Oleuropein has some amazing antioxidant and neuroprotective properties but it also contains cardioprotective properties as well.  Another 2017 study showed that a dosage of 60mg/kg/day of Oleuropein significantly reduced blood pressure over an 8-week period (3). Having such a profound effect on blood pressure, many individuals suggest supplementing oleuropein or oleuropein containing foods into their diet as a treatment of mild-moderate hypertension before seeking out the use of prescription medication.  One of the ways that oleuropein was found to aid in blood pressure regulation was through protection of the hypothalamus.  It was found that oleuropein protects the hypothalamus from oxidative stress and improves mitochondrial function in a biological pathway.  Because the hypothalamus is the part in the brain that controls homeostatic systems (keeping our bodies regulated properly), the introduction of oleuropein can actually benefit those who are already suffering from hypertension, not just those who are at risk for it!  With regards to exercise, oleuropein can play a big role in regulating blood pressure during and after our workouts as well.  Let’s face it, the heart is a muscle and if we don’t work it out regularly, we run the risk of having cardiovascular problems at some point in our life.  For individuals who may not be physically fit, oleuropein provides some stability with regards to blood pressure when partaking in physical activity and can help blood pressure remain regulated during that time. This is why supplementing with a clinically tested dose of oleuropein such as the amount in a serving of GlycoShield can play a bigger role than you think!


    Prevention of weight gain:

    As if the other properties of oleuropein weren’t enough, even more studies have been conducted on the ability of this compound to prevent weight gain, specifically fat gain from a high fat diet.  A 2014 8-week study suggests that olive leaf extract can prevent high-fat diet induced obesity as well as reduction in visceral fat weight gain and increase in plasma lipid levels (4).  Olive leaf extract does this by regulating the expression of genes involved in adipogenesis and thermogenesis in the visceral adipose tissue.  By regulating those properties, olive leaf extract can regulate both the amount of fat stored and our body temperature.  It is important to note here that while this study did not directly impact weight loss, it prevented weight gain when a high fat diet was consumed.  This makes oleuropein an especially important ingredient in GlycoShield when looking at its multi-dimensional use.  While we have mentioned that GlycoShield is a great product when it is used for recomposition and weight-loss goals, this facet makes it a great tool to prevent excess fat gain when bulking and trying to put on lean muscle mass!  We have all been there; trying to put on a few pounds of muscle before slimming down for the summer.  After consuming about 2500 calories of chicken and rice, that new pizza place is looking mighty tasty and before you know it, you’ve been eating everything in sight for the last 2 weeks!  This is where oleuropein becomes your ally in your body composition goals.  While we don’t recommend you cheat every day, with the Shielded Stack, you can if you want to!





    1: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392257/

    2: https://www.ncbi.nlm.nih.gov/pubmed/29099642

    3: https://www.ncbi.nlm.nih.gov/pubmed/27847271

    4: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927866/